Trait Discovery/Bioinformatics Lead

Other jobs >> General

Negotiable

Permanent

Description

About us

Calyxt (NASDAQ: CLXT), based in Roseville, Minnesota is a plant-based

technology company. We partner with like-minded farmers and companies to

deliver plant-based products with wellness and sustainability benefits. We use

cutting edge plant breeding techniques to innovate and develop solutions to

address unmet consumer and market demands. For further information, please

visit our website at .



Calyxt and the corporate logo are trademarks owned by Calyxt, Inc.



Job Summary

Calyxt is seeking a highly motivated and result-oriented scientific leader to

join our R&D organization. The individual will be responsible for developing

and implementing bioinformatics approaches to enable innovative gene discovery

and characterization of gene edits. The role will inform advancement decisions

of Calyxt products from discovery through product development phases. The

successful candidate will work in a team environment and interact with experts

in molecular biology, gene editing, plant transformation, breeding, and

regulatory affairs. S/he will also have a unique opportunity to work with

cross-functional teams as Calyxt gene edited products progress through the R&D

pipeline, comply with regulatory requirements and are brought to

commercialization.



Job Duties and Responsibilities

* Build-out trait discovery approaches and toolsets as well as broader

bioinformatics tools to support the gene editing & breeding platforms and

regulatory studies.

* Work as a player/coach member of the Trait Discovery team to help build

the team and provide scientific leadership to define approaches.

* Collaborate closely cross-functionally with scientists and plant breeders

to design experiments and continuously improve bioinformatics/data

analysis approaches to facilitate trait discovery, select edited events,

and support molecular breeding efforts.

* Build-out systems to analyze genomic sequences from a variety of

different sources.

* Develop workflows to process genomic data, develop and maintain internal

genome databases, genome browsers, and search tools.

* Interface with LIMS Architect/Administrator(s) to facilitate integration

of bioinformatics tools to the LIMS (e.g. sequence processing tools as

well as genomic and phenomic databases and analytic tools).

* Manage internal and external projects according to Calyxt s needs.

* Prepare data packages, reports and presentations to communicate with

stakeholders at various levels.

* Develop standard operating procedures (SOPs) to characterize Calyxt

edited lines.

* Provide training and troubleshooting for use of bioinformatics tools.

* Support regulatory studies as required.

* Other duties as required.



Qualifications

* PhD or MS plus 3 years of industry experience in Bioinformatics,

Computational Biology, Genomics or other related fields.

* Demonstrated experience in developing bioinformatics tools/pipelines and

data analysis strategies is required.

* Experience analyzing large genomic datasets and/or other omics

datasets is required.

* Demonstrated experience in forward genetics approaches for trait

discovery is required (e.g. genetic mapping, QTL analysis, GWAS).

* Demonstrated experience with genome assembly and annotation is preferred;

experience with polyploid genomes and/or phased assemblies is a plus.

* Ability to design and analyze transcriptomic experiments.

* Experience working with sequence analysis software (e.g. Geneious,

VectorNTI) and genome browsers (e.g. IGV, JBrowse) is required.

* Experience working in the cloud environment (AWS, Azure) is preferred.

* Familiarity with several languages (e.g. python, pearl, R) and working

knowledge of relational databases and SQL practice is preferred.

* Experience in one or more areas of advanced analytics preferred (e.g.

advanced statistical analysis & modeling, machine learning, or artificial

intelligence).

* Solid organizational and time management skills to ensure successful and

timely documentation and completion of projects.

* Excellent verbal and written communication skills and the ability to work

in a team environment to achieve project goals.



Contact:Please send resume and motivation letter to
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  • Negotiable
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  • Re-87051
  • Permanent
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