Data Scientist

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The Job Details are as follows:

What we do

United Therapeutics Corporation focuses on the strength of a balanced, value-creating biotechnology model. We are confident in our future thanks to our fundamental attributes, namely our commitment to quality and innovation, the power of our brands, our entrepreneurial culture and our bioinformatics leadership. We also believe that our determination to be responsible citizens having a positive impact on patients, the environment and society will sustain our success in the long term.

We currently have five approved products on the market and a long-term mission of providing an unlimited supply of transplantable organs for those who need them.

Our company was founded by an entrepreneur whose daughter was diagnosed with a life-threatening condition. She sought to find treatment options and a cure for her daughter and patients like her. We are founder-led, and relentless in our pursuit of medicines for life. We continue to research and develop treatments for cardiovascular and pulmonary diseases, pediatric cancers and other orphan diseases.

How youll contribute

We are looking for a Data Scientist to join our Computational Lab for In Silico Molecular Biology (CLIMB) team in Silver Spring Maryland. CLIMB is building a computational model of the lung to enable in silico design and testing of therapies for lung disease. In this role, you will mine molecular datasets and other databases to identify pathways and behavior governing lung function and therapeutic response to develop an integrative multiscale lung model.

- Analyze and interpret high-dimensional molecular datasets to identify biological processes/pathways relevant to lung physiology and pathology, and apply this information to discover drug targets and infer mechanism of action

- Conduct research into suitable machine learning approaches for deriving insights from molecular datasets through gene regulatory network inference, dimensionality reduction, clustering, or supervised learning

- Integrate biological knowledge from diverse sources, such as pathway databases, protein interaction networks, ontologies, and functional assays, to enhance interpretation of molecular datasets

- Collaborate with other computational biologists and engineers to integrate models into large multiscale models spanning processes from organ to molecular level

- Communicate results effectively through interactive visualizations, presentations at internal and external meetings, and peer-reviewed publications

- Other duties as assigned

For this role you will need

Minimum Requirements

- Bachelors or Masters degree in computational biology, applied mathematics, or related field of study

- 2+ years of industry experience (postdoctoral experience at a pharmaceutical/biotech company is acceptable)

- Expertise in machine learning methods applied to high-dimensional molecular datasets

- Fluency in one or more scientific programming languages (e.g. Python, R, Julia, and/or MATLAB)

- Experience with common databases and tools relevant to bioinformatics and systems biology

- Strong data visualization skills, including interactive visualization (e.g. R Shiny or d3.js)

- Ability to communicate effectively with both technical and non-technical audiences as demonstrated by record of presentations and publications

- Ability to travel up to 10%

Preferred Qualifications

- Ph.D. in computational biology, applied mathematics, or related field of study

- 6+ years of industry experience (postdoctoral experience at a pharmaceutical/biotech company is acceptable)

- Familiarity with quantitative systems pharmacology and other applications of modeling and simulation within pharmaceutical drug discovery and development

- Experience with imaging (CT, MRI) data

- Knowledge of molecular/cellular biology, pulmonary physiology, and drug development

Life as a Unitherian

At United Therapeutics, youll realize quickly that it is not an ordinary place to work! When you join our company, you will learn, grow, contribute, have fun, and be challenged... all while making a difference in the lives of our patients.

United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities
  • 1
  • Negotiable
  • None
  • None
  • Re-96908
  • Permanent
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